significance of adenosine deaminase in diagnosing tuberculous pleural effusion

 

 

 

 

Keywords Pleural Fluid. Adenosine Deaminase. Tuberculous Pleural Effusion. By following authors. Sharmeen Ahmed. Adenosine deaminase in the diagnosis of tuberculous pleural effusions: a report of 218 patients and review of the literature. Chest. Vol. 99.Adenosine deaminase in body fluids: A useful diagnostic tool in tuberculosis (1988) Segura R.M et al. Diagnostic significance of ada (adenosine deaminase) in tuberculous pleural effusion. Kalpana K. Dave, Nikunj V. Mehta, R.N. Gonsai, Dimple J. Dangia Department of Pathology, B. J. Medical College, Ahmedabad, Gujarat, India. Aims: The aim of the present study was to evaluate the efficiency of pleural fluid Adenosine Deaminase (ADA) levels in differential diagnosis of pleural effusions like to differentiate between tuberculous and non tuberculous effusions J Ayub Med Coll Abbottabad 200921(1). Diagnostic significance of adenosine deaminase in pleural tuberculosis.Methods: Fifty male and fifty female patients presenting with tuberculous pleural effusion was included in the study.

Light RW, Lazarus AA, McKay S, Gilbert R. Update on tuberculous pleural effusion. Respirology. 201015(3):451-8.Sharma SK, Suresh V, Mohan A. A prospective study of sensitivity and specificity of adenosine deaminase in the diagnosis of tubercular pleural effusion. All those with tuberculous pleural effusion had a pleural fluid adenosine deaminase level of 100 U/L. When analysis was restricted to 689 patients with pleural fluidSignificance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Chest 1994106:33-7. CrossRef. They lenge of diagnosing a pleural effusion of unknown release ADA when stimulated in the presence of live origin.

intracellular microorganisms.3 ForDiagnostic level should not be considered as an equivalent to value of pleural fluid adenosine deaminase in tuberculous the presence of Abstract. Adenosine deaminase (ADA) can aid in the diagnosis of tuberculous pleural effusions, but false-positive findings from lymphocytic effusions have been reported. Study of adenosine deaminase levels in the diagnosis of tuberculous pleural effusion.Results: In our study, all the parameters were elevated in disease condition that was tuberculous pleural effusion compared to non-tuberculous pleural effusion. Adenosine deaminase in the diagnosis of tuberculous pleural effusion.Tuberculous pleural effusion: twenty year experience. Chest 19911999:883-886 7. Roth BJ searching for tuberculosis in pleural space.Chest 1999:116:3-5 8. Bothamley GH. Tuberculosis is a major cause of pleural effusion, in which pleural fluid usually has lymphocytic and exudative characteristic. Accurate and early diagnosis of tuberculous pleurisy is essential for its correct treatment and management in clinical practice. Significance of Adenosine Deaminase Levels in Diagnosis of Pleural Effusion.Adenosine deaminase activity level as a tool for diagnosing tuberculous pleural effusion. Nathapol Khow-Ean, Suchart Booraphun, Noppadol Aekphachaisawat, Kittisak Sawanyawisuth. Keywords Adenosine deaminase Lung cancer Malignant pleural effusion Pleural biopsy Tuberculous pleural effusion Introduction Tuberculous pleural effusion (TPE) is still difficult to diagnose, especially in regions with a low incidence of tuberculosis. Abstract. Diagnosis of tuberculous pleural effusion (TPE) is difficult because of its non-specific clinical presentation and insufficient efficiency of conventional diagnostic methods. The study was carried out to evaluate the utility of adenosine deaminase (ADA) Pleural fluid ADA level was evaluated in all patients, and significance of pleural fluid ADA level in TB pleural effusion was studied.Adenosine deaminase in pleural fluids: test for diagnosis of tuberculous pleural effusion. Chest 1983 84: 51-3. 13. Valdes L, Alvarez D, Jose ES et al. Adenosine Deaminase Activity (ADA) is a commonly used marker for the diagnosis of tuberculous pleural effusion.11. Ungerer JP, Oosthuizen HM, Retief JH, Bissbort SH (1994) Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions . A polymerase chain reaction for tuberculous DNA may be done, or adenosine deaminase or interferon gamma levels may also be checked.Diagnosis. A large left sided pleural effusion as seen on an upright chest X-ray. A pleural effusion is usually diagnosed on the basis of medical Evaluation of Adenosine Deaminase (Ada) in Tuberculous Pleurisy. Adenosine deaminase (ADA) level in tubercular pleural effusion. Adenosine Deaminase: An Aid to Diagnose Tuberculosis. 11. Ungerer JP, Oosthuizen HM, Retief JH, Bissbort SH (1994) Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions .(2003) Diagnostic value of adenosine deaminase in tuberculous pleural effusion: a meta-analysis. Diagnosing tuberculous pleural effusion using clinical data and pleural fluid analysis: A study of patients less than 40 years-old in an area with a high incidence of tuberculosis.Diagnostic role of pleural fluid adenosine deaminase in tuberculous pleural effusion. PURPOSE: We examined the usefulness of adenosine deaminase 2 (ADA2) in the diagnosis of tuberculous pleuritis. SUBJECTS: A hundred cases, 78 male and 22 female, with pleural effusion were examined. Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions.Adenosine deaminase in the diagnosis of tuberculous pleural effusion: is it really an ideal test: a word of caution. J Microbiol Infect Dis 2013 3(3): 104-108 Key words: adenosine deaminase, sensitivity, specificity, diagnostic significance, tuberculous peritonitis.15. Maartens G, Bateman ED. Tuberculous pleural effusions in-creased culture yield with bedside inoculation of pleural fluid and poor Diagnostic significance of immunoglobulins and adenosine deaminase in pleural effusion. J. Assoc. Physicians India 47: 787-790.Adenosine deaminase in the diagnosis of tuberculous pleural effusion. Chest, 120: 334-336. Diagnostic value of adenosine deaminase in tuberculous pleural effusion: a meta-analysis.Diagnoses of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma. Valdes, L. San Jose, E. Alvarez, D. Sarandeses, A.

Pose, A. Chomon, B. Tuberculous Pleural Effusion | InTechOpen, Published on: 2013-03-20. Authors: Wolfgang Frank.50 - Ungerer JPJ Oosthuizen HMRetief JH Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. adenosine deaminase, sensitivity, specificity, diagnostic significance, tuberculous peritonitis.Tuberculous pleural effusions in- creased culture yield with bedside inoculation of pleural fluid and poor diagnostic value of adenosine deaminase. Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?Diagnostic accuracy of adenosine deaminase in tuberculous pleurisy: a meta-analysis. An exudative effusion is diagnosed if the patient meets Lights criteria. The serum to pleural fluid protein or albumin gradients may help better categorize27. Goto M, Noguchi Y, Koyama H, Hira K, Shimbo T, Fukui T. Diagnostic value of adenosine deaminase in tuberculous pleural effusion: a Introduction Previous studies have assessed the diagnostic ability of pleural fluid adenosine deaminase (pfADA) in detecting tuberculous pleural effusions, with good specificity and sensitivity reported. 24 ascites cases were studied by Gupta V. Significance of ADA activity and its isoenzymes (ADA-1m. The ADA activity in the tuberculous patients was significantly higher than in the other1: 751 754. Isoenzymes of adenosine deaminase in pleural effusions: a diagnostic tool. Thorax 1995 June. Table 2. Total adenosine deaminase (ADA) and adenosine deaminase isoenzyme 2(ADA2) activities of pleural fluids in diagnosed subgroups.Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Pleural effusion (PE) adenosine deaminase (ADA) has good performance in detection of tuberculous pleural effusion (TPE). However, few study was conducted for its value in pediatric patients. Study of adenosine deaminase as a biochemical marker of cell mediated immunity in tuberculous meningitis, tuberculous pleural effusion and tuberculous ascites.Diagnostic significance of pleural fluid adenosine deaminase activity in tuberculous pleurisy. Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Chest 1994106(1):33-37. [Medline] [CrossRef].Laniado-Laborin R. Adenosine deaminase in the diagnosis of tuberculous pleural effusion: is it really an ideal test? Adenosine deaminase in pleural fluids: test for diagnosis of tuberculous pleural effusion. Chest 1983 84: 5153.Ungerer JP, Oosthuizen HM, Retief JH, Bissbort SH. Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Pleural Fluid Adenosine Deaminase Values in Diagnosis of Tuberculous Pleural Effusion in South Khorasan Province.Objectives: The purpose of the present study was to evaluate the values of pleural fluid ADA in diagnosis of Tuberculous pleural effusion in South Khorasan province. Some features of this site may not work without it. Isoenzymes of adenosine deaminase in pleural effusions: A diagnostic tool?They consisted of 87 tuberculous effusions, 27 infective effusions (12 empyematous and 15 non-empyematous), 37 malignant effusions and six other exudative [13] Devkota KC, Shyam BK, Sherpa K, Ghimire P, Sherpa MT, Shrestha R and Gautam S. Significance of adenosine deaminase in. diagnosing tuberculous pleural effusion. Nepal Med Coll J 2012 14(2): 149-152. In this context, pleural fluid Adenosine Deaminase (ADA) level has been proposed as easy, cheap and highly sensitive test for diagnosis of TB pleural effusion.Almost all patients diagnosed to have TB pleural effusion responded completely to anti- tubercular treatment. Adenosine Deaminase in the diagnosis of Tuberculous Pleural Effusion.Significance of Adenosine Deaminase Activity and its Isoenzymes in Tuberculous effusions. Chest 106:33-37. Seibert AF, Haynes J Jr, Middleton R, Bass JB Jr, et al (1991). Conclusion:: Pleural fluid ADA remains useful in diagnosing tuberculosis pleural effusion.Vol 9: Diagnostic accuracy of adenosine deaminase for tuberculous peritonitis: a meta-analysis.Vol 54: Diagnostic Value and Prognostic Significance of Pleural C-Reactive Protein in Lung Cancer Keywords. Tuberculous pleural effusion Malignant pleural effusion Differential diagnostic significance Tumor necrosis factor-alpha Interferon-gamma Interlukine-10 Adenosine deaminase 2. Sig-nificance of adenosine deaminase activity and its isoen-zymes in tuberculous effusions.deaminase in the diagnosis of tubercular pleural effusion. Indian J Chest Dis Allied Sci 200143:149-155 12. Tuberculous pleural effusion (TPE) is a common problem for differential diagnosis from malignant effusion (MPE) in epidemic areas of tuberculosis (TB). Prediction based on adenosine deaminase (ADA) is dependent on age as well as the tuberculosis incidence. OBJECTIVE: Pleural effusion (PE) adenosine deaminase (ADA) has good performance in detection of tuberculous pleural effusion (TPE). However, few study was conducted for its value in pediatric patients. Tuberculous pleural effusion was diagnosed in 50 patients (37.9).Substances. Adenosine Deaminase. PubMed Commons home. Abstract Introduction: Adenosine deaminase (ADA) is a useful biochemical parameter for tuberculous pleural effusion. Studies have confirmed diagnostic role of Adenosine deaminase for early diagnosis of pleural tuberculosis in high prevalence countries like India. The diagnostic utility of adenosine deaminase isoenzymes in tuberculous pleural effusions.Setting: Pleural adenosine deaminase (ADA) levels have been found to be useful in diagnosing tuberculous pleuritis.

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